Table of Contents
Is diacetyl Boldine safe for skin?
It provides full UVA / UVB protection and prevents the appearance of new pigmentation. After 56 days with twice daily use of Diacetyl-boldine your skin is visibly illumined. The product is perfectly tolerated even by very sensitive skin.
What is diacetyl Boldine?
Extracted from the bark of Chilean Boldo trees, Diacetyl Boldine is an antioxidant that is known to treat excess pigmentation concerns including sunspots, hyperpigmentation, and melasma by inhibiting Tyrosinase, an enzyme responsible for melanin production.
What is Lumiskin?
Lumiskin™ is a solution of diacetyl-boldine and caprylic/capric triglycerides that inhibit the activity of tyrosinase. It is used for its skin lightening properties. Diacetyl Boldine (DAB) works well via a-adrenergic antagonist receptors and calcium flow regulation.
What is Octadecenedioic acid?
Octadecenedioic acid is derived from sunflower seeds and is structurally similar to azelaic acid. One of the things that makes it such a potentially interesting cosmetic active is its ability to lighten the skin, fading dark spots and hyperpigmentation.
What is Tyrostat?
Tyrostat™ is a natural skin whitening agent from Rumex species native to Northern Canada. It is edible, safe and globally registered. Tyrostat™ inhibits Tyrosinase and has a similar activity to Kojic acid.
What is Kojic acid derived from?
Kojic acid is a fungal metabolic product produced by a few species of Aspergillus, especially by A. oryzae, which has the Japanese common name koji. This acid is a by-product in the fermentation process of malting rice, for use in the manufacturing of sake, the Japanese rice wine.
What is Octadecenedioic acid used for?
This acid brightens skin by decreasing tyrosinase and melanin (skin pigment) production. It can be used to treat skin pigmentation problems such as dark spots, hyper-pigmentation, and melasma.
What is rumex occidentalis extract?
Rumex occidentalis Extract Melasma is a difficult-to-treat pigmentation disorder that predominantly affects women. 14,15. In a randomized, double-blind, placebo-controlled trial, Rumex occidentalis extract was found to be as effective as the gold-standard skin-lightener hydroquinone in the treatment of melasma.
What Tyrostat 11?
Tyrostat™ 11 is a potent strong inhibitor of tyrosinase enzymatic activity, one of the main enzymes involved in the pigmentation process. It has higher activity than arbutin, turmeric and hydroquinone and with no unwanted side effects.
Does azelaic acid darken skin?
Azelaic acid lightens hyperpigmentation by reducing melanin production in hyperactive areas (darker spots on the skin). Azelaic acid limits melanin creation by inhibiting tyrosinase, an enzyme needed for the production of melanin in your skin.
What is Diglucosyl gallic acid?
Diglucosyl Gallic Acid is a molecule derived from biotechnology that is then activated through the skin’s microbiome. Its properties include skin-brightening, anti-inflammatory and photo-protection, all targeted around reducing the development of pigment and keeping the skin visibly bright and even.
What is cysteamine cream?
Cysteamine 5% cream (Cysteamine Cream®, ScientisPharma) is a skin-lightening agent used in the treatment of hyperpigmentation disorders such as melasma, postinflammatory hyperpigmentation and lentigines. It has also been used to lighten skin colour overall. It is available as a 50-g tube.
Is kojic acid cancerous?
Kojic acid was not a toxicant in acute, chronic, reproductive, and genotoxicity studies. While some animal data suggested tumor promotion and weak carcinogenicity, kojic acid is slowly absorbed into the circulation from human skin and likely would not reach the threshold at which these effects were seen.
Will azelaic acid lighten skin?
Products containing azelaic acid can be used to treat hyperpigmentation. This is because azelaic acid inhibits the enzyme tyrosinase, which is needed for the production of melanin. By affecting melanin production, azelaic acid has the ability to lighten the skin and reduce the appearance of hyperpigmentation.
Is azelaic acid better than hydroquinone?
Conclusions: In conclusion, this study suggests that 20% azelaic acid cream applied twice daily may be more effective than hydroquinone 4% in reducing mild melasma.
How effective is diacetyl boldine for melasma?
Combined Use of Two Formulations Containing Diacetyl Boldine, TGF-β1 Biomimetic oligopeptide-68 With Other hypopigmenting/exfoliating Agents and Sunscreen Provides Effective and Convenient Treatment for Facial Melasma. Either Is Equal to or Is Better Than 4% Hydroquinone on Normal Skin
What are whitening agents used to treat?
They are also utilized for clinical treatment of pigmentary disorders such as melasma or postinflammatory hyperpigmentation. Whitening agents act at various levels of melanin production in the skin.
Can ascorbyl glucoside be used to whiten skin?
Ascorbic acid is considered a skin whitening agent and more stable derivatives such as ascorbyl glucoside and ascorbyl palmitate are already being used in different skin whitening formulations [73]. As known from many cases of post-inflammatory hyperpigmentation, melanogenesis can be stimulated by some inflammatory mediators.