What is Biacore T100?

What is Biacore T100?

Biacore T100 can be used to monitor almost any molecular interactions as long as one of the interacting partner can be immobilized on a sensor surface. It characterizes molecules in terms of the specificity of interaction, on and off -rates (kinetics), binding strength (affinity) and thermodynamics.

What is Biacore technology?

The Biacore platform monitors molecular interactions in real time by using a non-invasive label-free technology. This technology reacts to changes in the concentration of molecules at the sensor surface as molecules bind to or detach from the surface.

What is SPR sensor?

Surface plasmon resonance (SPR) sensor is now being utilized to detect the change of refractive index and, therefore, the mass density in accordance with molecular association or dissociation near the surface of thin metal layer.

What does Biacore measure?

SPR (Biacore) assays provide a method for determining the affinity and binding kinetics of a ligand for its receptor. The technique measures the real-time binding association and dissociation rates using Surface Plasmon Resonance (SPR).

What is Biacore analysis?

Biacore is used by BioAgilytix in immunogenicity studies to analyze and characterize anti-drug antibodies (ADAs) and molecular interactions related kinetics, specificity, and concentration.

How much does an SPR machine cost?

We specialize in SPR and Local SPR devices and our device prices start at $4500. Range of SPR model includes 2 and 8 channel SPR models as well as Local SPR device.

What can SPR tell you?

SPR directly detects mass (concentration) with no need for special radioactive or fluorescent labeling of polypeptides (5) before measurement, presenting a great advantage in minimizing time and complexity of the studies.

What is OpenSPR?

OpenSPR is the world’s only benchtop surface plasmon resonance (SPR) instrument. It provides high quality, label-free interaction analysis for a fraction of the cost of existing solutions. Our unique nano-structured sensor surface uses localized SPR (LSPR) to deliver repeatable, highly sensitive kinetic data.

Why is gold used in SPR?

In most cases, gold is used because it gives a SPR signal at convenient combinations of reflectance angle and wavelength. In addition, gold is chemically inert to solutions and solutes typically used in biochemical contexts (1).